Signalling crosstalk
نویسندگان
چکیده
منابع مشابه
Crossing paths: cytokinin signalling and crosstalk.
Cytokinins are a major class of plant hormones that are involved in various aspects of plant development, ranging from organ formation and apical dominance to leaf senescence. Cytokinin and auxin have long been known to interact antagonistically, and more recent studies have shown that cytokinins also interact with other plant hormones to regulate plant development. A growing body of research h...
متن کاملSignalling crosstalk in plants: emerging issues.
The Oxford English Dictionary defines crosstalk as 'unwanted transfer of signals between communication channels'. How does this definition relate to the way in which we view the organization and function of signalling pathways? Recent advances in the field of plant signalling have challenged the traditional view of a signalling transduction cascade as isolated linear pathways. Instead the pictu...
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Wild-type p53 and TGF-β are key tumour suppressors which regulate an array of cellular responses. TGF-β signals in part via the Smad signal transduction pathway. Wild-type p53 and Smads physically interact and coordinately induce transcription of a number of key tumour suppressive genes. Conversely mutant p53 generally subverts tumour suppressive TGF-β responses, diminishing transcriptional act...
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The remarkable plasticity of plant ontogeny is shaped by hormone pathways, which not only orchestrate intrinsic developmental programs, but also convey environmental inputs. Several classes of plant hormones exist, and among them auxin, brassinosteroid and gibberellin are central for the regulation of growth in general and of cell elongation in particular. Various growth phenomena can be modula...
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We propose a general theory of cooperativity between transmembrane receptors of a cell. Based on a conformation-dependent interaction between nearest-neighboring receptors, the sensitive signalling and the enhancement of clustering, or oligomerization, are explained as two responses to ligand binding. In this model, ligand binding shifts the energy difference between the two conformational stat...
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ژورنال
عنوان ژورنال: Nature Reviews Molecular Cell Biology
سال: 2006
ISSN: 1471-0072,1471-0080
DOI: 10.1038/nrm1864